HEPATOPROTECTIVE ACTIVITY OF VITEX NEGUNDO LINN. BY PARACETAMOL INDUCED HEPATOTOXICITY IN RATS
نویسندگان
چکیده
منابع مشابه
Pharmacokinetic-interaction of Vitex negundo Linn. & paracetamol.
BACKGROUND & OBJECTIVES Currently, herbal preparations are clinically used as functional food, food supplements or as add on therapy, which affects the bioavailability and also the net therapeutic potential of co-administered allopathic drugs. Therefore, it is important to assess the interaction among these two classes of drugs. Here we studied the interaction between orally-administered ethano...
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The present study was conducted to evaluate the hepatoprotective activity of hydroalcoholic extract of Tabernaemontana divaricata Linn.against paracetamol induced liver damage in rats. The hydroalcoholic extract of Tabernamontana divaricata Linn. (600mg/kg) was administered orally to the animals with hepatotoxicity induced by paracetamol (3gm/kg). Silymarin (25mg/kg) was given as reference stan...
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Liver diseases such as jaundice, cirrhosis etc. are very common worldwide and traditional medicine are proving to be useless or less effective against them. Therefore workers are trying to find out alternate medicine or formulations to combat these diseases. In the present study hepatoprotective activity of aqueous extract of Adhatoda vasica and Vitex negundo on total protein, bilirubin, aspart...
متن کاملComparative Study of the Hepatoprotective Activities of Vitex Negundo Linn. and Moringa Oleifera Lam. in Paracetamol Induced Hepatotoxicity in Experimental Animals
Aims: To evaluate the hepatoprotective activity of Vitex negundo Linn. and Moringa oleifera Lam. In paracetamol induced hepatotoxicity in rats. Materials and Methods: Liver damage was induced in 42 albino rats by paracetamol (1 g/kg P.O.) once daily for a period of 7 days. Silymarin was taken as the standard drug in a dose of 25 mg/kg P.O. Albino Wistar rats (150-200 g) were divided into groups...
متن کاملEvaluation of hepatoprotective and antioxidant activity of Ichnocarpus frutescens (Linn.) R.Br. on paracetamol-induced hepatotoxicity in rats
Purpose: The entire plant including the flowers, of Ichnocarpus frutescens R.Br. (Apocynaceae) has been used for the treatment of cancer, skin infections, diabetes and liver disorder. The present study is aimed at evaluating the hepatoprotective effect of chloroform and methanol extract (CEIF and MEIF) of whole plant of I. frutescens (Linn.) by paracetamol-induced liver damage in rats. Methods:...
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ژورنال
عنوان ژورنال: International Journal of Pharmacological Research
سال: 2011
ISSN: 2277-3312
DOI: 10.7439/ijpr.v1i1.148